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Study Results Raise Questions About Vertebroplasty For Patients With Osteoporotic Spinal Compression Fractures
A new study led by Mayo Clinic researchers has found that relief of pain from vertebral compression fractures, as well as improvement in pain-related dysfunction, were similar in patients treated with vertebroplasty and those treated with simulated vertebroplasty without cement injections. The article, "A Randomized Controlled Trial of Vertebroplasty for Osteoporotic Spine Fractures," was released today in the New England Journal of Medicine.
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SOS Research Project Assesses The Cardiovascular And Gastrointestinal Risk Related To The Use Of Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Medical information of more than 35 million persons from the general European population will be studied with the goal of better guiding clinicians how to balance the risk of gastrointestinal and cardiovascular events when prescribing NSAIDs.
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Back To Normal: Surgery Improves Outcomes For Spine Patients
People with the spine disease called degenerative spondylolisthesis -- who choose surgical treatment -- experience substantially greater relief from pain over time compared to those who do not have surgery, according to a study published in the June 2009 issue of The Journal of Bone and Joint Surgery (JBJS). In the past, physicians had been uncertain whether surgery provided significantly greater relief for patients, but these results help to confirm the advantages to surgery.
Oncology

The Risk Factors For Sporadic Colorectal Cancer

Colorectal cancer (CRC) is one of the most common cancers in China. Although the association between the epidemiological factors and sporadic colorectal cancer has been studied, the relation between smoking, alcohol drinking, family history of cancer, body mass index (BMI) and sporadic colorectal cancer still remains uncertain. So it is important to investigate the role of these factors in the development of sporadic colorectal cancer. A research team led by Professor Jian-Ping Wang from the Gastrointestinal Institute of Sun Yat-Sen University addressed this question. Their study was published in the World Journal of Gastroenterology. They conducted a hospital-based case-control study from July 2002 to December 2008 in Guangzhou city. There were 706 cases and 723 controls with their sex and age (within 5 years) matched. An unconditional logistic regression model was used to analyze the association between smoking, alcohol drinking, family history of cancer, BMI and sporadic colorectal cancer. They found that current alcohol drinking and greater BMI (ò‰¥ 24.0 kg/m2) are the independent risk factors for colon and rectal cancer, while former alcohol drinking and positive family history of cancer are the independent risk factors for colon cancer in southern Chinese. Their findings may contribute to the prevention and control of sporadic colorectal cancer. However, because of the uncontrolled bias in selection participants and retrospective design, their findings need to be further evaluated in well-designed larger epidemiological studies with different ethnic populations. Reference: Wei YS, Lu JC, Wang L, Lan P, Zhao HJ, Pan ZZ, Huang J, Wang JP. Risk factors for sporadic colorectal cancer in southern Chinese. World J Gastroenterol 2009; 15 (20): 2526-2530. Correspondence to: Jian-Ping Wang, Professor, MD, Gastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, Yuancunerheng Road 26, Guangzhou 510655, Guangdong Province, China. Lai-Fu Li World Journal of Gastroenterology


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