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Study Rewrites Textbook On Key Genetic Phenomenon
Because females carry two copies of the X chromosome to males" one X and one Y, they harbor a potentially toxic double dose of the over 1000 genes that reside on the X chromosome.
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FDA Accepts For Review Spectrum's Response On ZEVALIN As A Class 1 Submission, And Establishes September 7, 2009 As Decision Date
Spectrum Pharmaceuticals, Inc. (NasdaqGM: SPPI), a commercial stage biotechnology company with a focus on oncology, announced that the U.S. Food and Drug Administration (FDA) has accepted for filing and review the resubmission to the Company"s supplement to the biologics license application for ZEVALIN (ibritumomab tiuxetan) in the first line consolidation setting on July 8, 2009. The FDA considers the review as a Class 1 submission to their complete response letter of July 2, 2009. Therefore, the user fee goal date is September 7, 2009.
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Vimpat(R) (lacosamide) C-V, A New Antiepileptic Drug (AED), To Be Available In U.S. Pharmacies
Vimpat(R) (lacosamide) C-V, a new antiepileptic drug (AED), will be available in U.S. pharmacies by the first week of June 2009. Vimpat was approved by the U.S. FDA in the fall of 2008 for the use as an add-on therapy for the treatment of partial-onset seizures in people 17 years and older with epilepsy.
Oncology

Risk Of Low Birth Weights Reduced By Multivitamins In Pregnancy

Prenatal multivitamin supplements are associated with a significantly reduced risk of babies with a low birth weight compared with prenatal iron-folic acid supplementation, found a new study in the Canadian Medical Association Journal (CMAJ). The World Health Organization currently recommends iron-folic acid supplements for all pregnant women. Previous studies have not shown an advantage from prenatal multimicronutrient supplementation over iron-folic acid supplementation. "Low birth weight and related complications are considered the most common cause of global infant mortality under the age of 5 years," write Dr. Prakash Shah and study coauthors from Mount Sinai Hospital in Toronto. "With the possibility of reducing low birth weight rates by 17%, micronutrients supplementation to pregnant women, we believe, offers the highest possible return for the investment. These results are synthesized findings from 15 studies published worldwide." It is estimated that of the total 133 million births worldwide per year, 15.5% are low birth weight babies. The authors suggest that approximately 1.5 million babies born with a low birth weight could be avoided each year globally, if all mothers receive prenatal multimicronutrient supplementation. The research is limited by variability among the included studies, including timing, duration, composition of micronutrients, and characteristics of the study populations. In a related commentary http://www.cmaj.ca/press/pg1188.pdf, Dr. Zulfiqar Bhutta and Dr. Batool Azra Haider of the Aga Khan University in Karachi, Pakistan recommend that multimicronutrient supplementation during pregnancy replace iron and folate supplements in susceptible populations if it is proven safe and effective. They note that multiple interventions in developing countries may be necessary to improve maternal nutrition and fetal status such as fortified food supplements, interventions that address specific nutrient deficiencies, and measures to reduce the burden of HIV, malaria and other diseases. Kim Barnhardt Canadian Medical Association Journal


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