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Cloud Computing Brings Cost Of Protein Research Down-to-earth
The amazingly powerful computers at Amazon.com - where online customers order books, CDs, and other products - are giving scientists an inexpensive tool to crunch massive amounts of data being generated by efforts to understand proteins. Termed proteomics, the large-scale study of all the proteins in an organism, promises new ways of diagnosing and treating hundreds of diseases. In a report scheduled for the June 5 issue of ACS" monthly Journal of Proteome Research, scientists describe the development of free tools using Amazon"s "cloud computing" service that can help shoulder scientists" data crunching needs with its brawny network of computers.
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Electronic Coding Overestimates Prevalence Of Barrett's Esophagus
In a review of more than 2,000 patients coded for Barrett"s esophagus, electronic diagnosis overestimated the prevalence of the disease according to researchers in California. They found that only 61.9 percent of patients assigned a billing diagnosis code for Barrett"s esophagus actually had Barrett"s esophagus after a manual record review. The study evaluated the accuracy of diagnostic codes for Barrett"s esophagus by contrasting codes from electronic databases with diagnoses from a detailed medical record review. Researchers also evaluated the reproducibility of a pathologic diagnosis of Barrett"s esophagus between two pathologists and between a single pathologist on two different occasions. The study appears in the May issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).
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ASGS Issues Position Statement Supporting TIF Natural Orifice Surgery For GERD
EndoGastric Solutions (EGS), the recognized leader in the emerging field of Natural Orifice Surgery (NOS), announced that the American Society of General Surgeons (ASGS) has published a position statement endorsing its Transoral Incisionless Fundoplication (TIF) procedure for the treatment of GERD. ASGS is the preeminent society of general surgeons with membership exceeding 2,000.
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No Psychological Risk In Children Next-Born After Stillbirth

There is no evidence that children next-born after stillbirth are clinically at risk compared to children of non-bereaved mothers, according to a study published in The Journal of Child Psychology and Psychiatry. However, the study did find evidence of less optimal mother-child interaction. Stillbirth can be a major psychological trauma to parents. Anecdotal accounts have suggested that children born subsequent to stillbirth of a sibling may be psychologically vulnerable. This study is the first systematically conducted case-control follow-up to examine this question and assessed first-time mothers from pregnancy until the children were aged six to eight years. At the time of the follow-up, there were 52 mothers in the study whose previous pregnancy had ended in stillbirth (the index group), and 51 who had not experienced stillbirth (the control group). The researchers found no significant between-group differences in child cognitive or health assessments, or in teacher-rated child difficulties. However, mothers in the index group reported increased child difficulties, in particular peer problems, and there were higher levels of maternal criticism of the child"s actions. "We found that bereaved mothers tended to identify more difficulties with their child than non-bereaved mothers, and that they reported more difficulties in the child than did teachers," said the paper"s lead author, Dr. Penelope Turton, of St George"s University of London. "Whether this was because previous loss of a child renders some mothers more sensitive to aspects of their child"s behaviour that cause them concern, or whether there is real variation in the child"s behaviour is unclear." Turton continued, "We are continuing to follow this group of mothers and children, and will follow-up again once the children reach adolescence. This type of study is very important in helping midwives, health visitors, and doctors to provide psychological care for both parents after a stillbirth and in the next pregnancy; while the severity of grief usually diminishes over the first one to two years, some mothers continue to experience more intense or prolonged grief and we need to know what long-term effects this can have." Jennifer Beal Wiley-Blackwell


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