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New Technology At Great Ormond Street Hospital Is Aiding Faster Emergency Referrals To Its Specialist Paediatricians, England
Thanks to the introduction of an innovative IT system at the Children"s Acute Transport Service (CATS) hosted at Great Ormond Street Hospital for Children NHS Trust (GOSH), referring hospitals can now share perfect quality medical data on emergency patients more quickly and securely than ever before.
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Lobbyists Play Ball, Flex Muscles On Health Care Reform
The Associated Press reports on lobbying around biotechnology legislation. A letter urging the protection of biotech drug makers from generics from "the private National Health Council, sent to House leaders drafting health overhaul legislation, said the plea was on behalf of "the more than 133 million Americans living with chronic diseases and disabilities and their family caregivers." It urged lawmakers to protect the makers of high-technology biological medicines against early competition from lower-cost generic copycats. The letter did not mention that nearly $1.2 million of the council"s $2.3 million budget in 2007 came from the pharmaceutical industry"s chief trade group and 16 companies that sell or are developing the brand-name biotech drugs."
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Damon Runyon Cancer Research Foundation Awards $2.7M To 7 Top Young Clinical Investigators
The Damon Runyon Cancer Research Foundation named 4 new Damon Runyon Clinical Investigators at its April 2009 Clinical Investigator Award Committee review. The recipients of this prestigious, three-year award are outstanding early career physician-scientists conducting patient-oriented cancer research at major research centers under the mentorship of the nation"s leading scientists and clinicians. Each will receive $450,000 to support the development of his cancer research program.
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New Method For Detecting Nitroxyl Will Boost Cardiac Drug Research

Wake Forest University scientists have developed a new research tool in the pursuit of heart medications based on the compound nitroxyl by identifying unique chemical markers for its presence in biological systems. Nitroxyl, a cousin to the blood-vessel relaxing compound nitric oxide, has been shown in studies to strengthen canine heart beats, but research into its potential benefits for humans has been slowed by a lack of specific detection methods. "I think this is a very powerful tool to help in the development of new drugs for congestive heart failure," said S. Bruce King, a professor of chemistry at Wake Forest who leads the team that conducted the research. Researchers can generate nitroxyl from precursor chemicals under controlled conditions, but studying the molecule"s activity in cells is difficult because its constituent elements-nitrogen, oxygen and hydrogen-react so readily with other molecules. King"s research team used compounds that are not present in normal cell biology to produce a reaction that yields the identifying chemical markers. King has been investigating nitrogen oxide compounds at Wake Forest since 1995. While scientists have established that the human body naturally produces nitric oxide, natural production of nitroxyl is suspected but has not been demonstrated. King said the new chemical markers could help answer that question, as well. The research is described in an article, "Reductive Phosphine-Mediated Ligation of Nitroxyl (HNO)," published online in the American Chemical Society"s journal Organic Letters. King co-authored the paper with Wake Forest graduate chemistry students Julie Reisz and Erika Klorig, and chemistry department staff member Marcus Wright, an instrumentation manager. King"s research team has received support from the National Institutes of Health, the National Science Foundation, the American Heart Association and the North Carolina Biotechnology Center. Wake Forest University


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