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Reprogrammed Mouse Fibroblasts Can Make A Whole Mouse
In a paper publishing online July 23 in Cell Stem Cell, a Cell Press journal, Dr. Shaorong Gao and colleagues from the National Institute of Biological Sciences in Beijing, China, report an important advance in the characterization of reprogrammed induced pluripotent stem cells, or iPSCs.
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Columnists Respond To Selection Of Sotomayor As Supreme Court Nominee
The New York Times, Washington Post and Washington Times recently published opinion pieces on President Obama"s nomination of Judge Sonia Sotomayor to the Supreme Court. Summaries appear below.~ David Brooks, New York Times: "Supreme Court justices, like all of us, are emotional intuitionists" because "they begin their decision-making processes with certain models in their heads," Times columnist Brooks writes, adding that "[t]hese are models of how the world works and should work, which have been idiosyncratically ingrained by genes, culture, education, parents and events," and which "shape the way judges perceive the world." Therefore, the "crucial question in evaluating a potential Supreme Court justice ... is not whether she relies on empathy or emotion, but how she does so," according to Brooks. He writes that Sotomayor "will be a good justice if she can empathize with the many types of people and actions involved in a case, but a bad justice if she can only empathize with one type, one ethnic group or one social class." He concludes, "It"s not whether judges rely on emotion and empathy, it"s how they educate their sentiments within the discipline of manners and morals, tradition and practice" (Brooks, New York Times, 5/29).~ Michael Gerson, Washington Post: By opposing Sotomayor"s confirmation, Republicans could be entering "a trap" by "further alienating Hispanic voters the GOP has recently driven away in droves," which might "confirm an image of Republicans as the party of the male and pale," columnist Gerson writes in a Post opinion piece. He continues, "Barring unforeseen ethical revelations, opposition to Sotomayor seems both politically risky and ultimately futile." However, "Republicans must still enter the trap -- with open eyes and no expectation of gain -- not to defeat a nominee but to maintain a principle" that the court "should be a place where all are judged impartially, as individuals," Gerson writes. He continues that the "Obama/Sotomayor doctrine of empathy challenges this long-established belief," and this "is not a minor matter." According to Gerson, "Concerns about the doctrine of empathy will not defeat Sotomayor -- and perhaps they should not defeat her." However, the "problems raised by selective empathy require a substantive (not harsh or personal) national debate -- and this requires Republicans to carefully, warily, enter Obama"s trap" (Gerson, Washington Post, 5/29).~ Michael Kinsley, Washington Post: "What conservative Republicans don"t like about the Supreme Court can be summarized as three, or maybe four, A"s: abortion, affirmative action and activism," columnist Kinsley writes in a Post opinion piece. He adds that "[r]ecent Republican platforms have pledged to appoint judges who not only will overturn Roe [v. Wade] but will make clear that fetuses have the same rights as people under the 14th Amendment"s guarantee of "equal protection of the laws."" Kinsley continues that supporters of Roe "clearly represent the "activist" side," while opponents of the decision "are right that Roe represents the highest tide of Warren Court activism." However, this "doesn"t mean the critics of Roe are right on the merits;" rather, it means that ""activism" is a near-worthless concept, and comparative activism is nonsense," Kinsley writes. He continues, "Although I am pro-choice, Roe makes me unhappy because it was poorly reasoned, not because it "went further" than other decisions." According to Kinsley, "many opponents of Roe would not be satisfied with merely seeing it overturned and the issue returned to the states," and, in fact, the GOP platform "effectively calls for a litmus test for judges: Will they rule abortion illegal in all 50 states no matter what the people want?" He continues, "Now that would be judicial activism with a vengeance" (Kinsley, Washington Post, 5/29).~ Eugene Robinson, Washington Post: The fact that Sotomayor "is a proud and accomplished Latina" apparently "drives some prominent Republicans into a s
News of the day
World Bank To Give Nigeria $100M Loan For Malaria Control
Nigeria on Monday signed on to receive a $100 million loan from the World Bank for malaria control activities, Leadership Nigeria reports. The states of Akwa Ibom, Anambra, Bauchi, Gombe, Jigawa, Kano and Rivers will receive part of the funding for malaria control activities (Nduwugwe, 7/21).World Bank Country Director for Nigeria Onno Ruhl signed the agreement on behalf of the bank and Nigerian Finance Minister Sarki Muhtar signed on behalf of the federal government. Ruhl said the World Bank is "confident" in Nigeria"s ability to fight malaria, This Day writes. Ruhl pointed out that during President Barack Obama"s recent trip to Ghana, he "commended" Nigeria"s interfaith efforts for fighting malaria.
Oncology

Joint Statement On Atypical Antipsychotic Use In Children

As advocates for people living with mental illnesses, we strongly urge the FDA to carefully consider the importance of viable treatment options for bipolar disorder and schizophrenia in pediatric and adolescent populations. Access to safe and effective treatments, including more information about all treatment options, is crucial to treating these serious and complex conditions in children and adolescents. Bipolar disorder and schizophrenia are very real, life-threatening diseases which can appear in childhood and adolescence. For example, federally funded research (STEP-BD) found that, of 3,658 adult patients studied, 68% reported bipolar disease onset in childhood or adolescence. Patients with child onset had, on average, fewer days of euthymia (or neutral mood), greater impairment in functioning and poorer quality of life. Those with adolescent onset have better outcomes than those with child onset, but were still worse off than those who did not suffer from bipolar disorder until adulthood. These alarming statistics highlight the need for early recognition and treatment, which offers children and adolescents their best chance to achieve and maintain wellness. We encourage an open and transparent scientific discourse about all pharmacologic treatments that come before the Advisory Committee and urge the Committee to carefully weigh the available evidence regarding safety and efficacy. No one treatment option works for all children. In order for physicians and families to make informed treatment decisions they need access to a full range of medications and treatment options and to the research regarding the risks and benefits of these treatments. More long-term clinical research in children and adolescents is also needed to better understand the risks and benefits of these medications when used over an extended period. As we know, these medications can also have serious side effects, which is why it is crucial that parents and physicians have as much information as possible in order to make informed decisions and weigh the risk of side effects and adverse reactions against the risk of not treating these very serious diseases. Other treatments for grave childhood illnesses such as cancer can cause hair loss, nausea, compromised immune systems and even death. However, few people question the necessity of these aggressive forms of treatment. Like cancer, aggressive treatment may be needed for some patients with bipolar disorder and schizophrenia, diseases with a higher risk of death than some forms of cancer. The best way to protect the health of our nation"s children and adolescents is to increase access to treatment options and communicate accurate, scientific information that helps parents and physicians cope with and properly treat these devastating illnesses. Our non-profit national mental health advocacy and medical professional organizations represent consumers, physicians, researchers and the top experts in the field of mental health and neuroscience. Mental Health America


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