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Faster, More Cost-effective DNA Test For Crime Scenes, Disease Diagnosis
Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR), a DNA test widely used in criminal investigations, disease diagnosis, biological research and other applications. The new method could lead to expanded use of PCR in medicine, the criminal justice system and elsewhere, the researchers say. Their study is scheduled for the July 15 issue of Analytical Chemistry, a semi-monthly journal.
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Expert Statement Issued About Lantus(R) Following Recent Publications In Diabetologia
Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced the release of an Expert Statement by a multidisciplinary board of renowned international experts following an in-depth assessment of the recent publications of registry analyses with Lantus(R) (insulin glargine [rDNA] injection) in Diabetologia. This board of international specialists in the field of endocrinology, oncology and epidemiology came to the conclusion, that all four manuscripts have significant methodological limitations and shortcomings, and that they provide inconsistent and inconclusive results regarding a potential link between insulin glargine use and an increased risk of cancer.
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Severe COPD May Lead To Cognitive Impairment
Severe chronic obstructive pulmonary disease (COPD) is associated with lower cognitive function in older adults, according to research from Mount Sinai School of Medicine. Researchers compared cognitive performance in over 4,150 adults with and without COPD and found that individuals with severe COPD had significantly lower cognitive function than those without, even after controlling for confounding factors such as comorbidities.
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Increase In Thyroid Cancer Not Explained By Screening Alone

Studies have reported an increasing incidence of thyroid cancer since 1980. One possible explanation for this trend is increased detection through more widespread and aggressive use of screening tests. Researchers at the American Cancer Society analyzed thyroid cancer incidence between 1988 and 2005 using the National Cancer Institute"s (NCI"s) Surveillance Epidemiology and End Results (SEER) dataset. They found incidence rates increased for all sizes of tumors, suggesting that screening is not the only explanation for the rise. The highest rate of increase was for primary tumors smaller than 1.0 cm, which rose nearly 10 percent per year among men from 1997 and 2005, and nearly 9 percent/year from 1988 to 2005 among women. Incidence of tumors 4 cm or larger increased more than 3.5 percent per year from 1988 to 2005 among men and 5.7 percent per year from 1988 to 2005 among women. The authors conclude that incidence rates of differentiated thyroid cancers of all sizes increased between 1988 and 2005 in both men and women, and that the increased incidence across all tumor sizes suggests that increased detection through testing is not the sole explanation. Other explanations, including environmental influences and molecular pathways, should be investigated. Article: "Increasing Incidence of Differentiated Thyroid Cancer in the US (1988-2005)." Amy. Y. Chen, Ahmedin Jemal, and Elizabeth M. Ward. CANCER; Published Online: July 13, 2009 (DOI: 10.1002/cncr.24416); Print Issue Date: August 15, 2009 American Cancer Society


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