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Study Examines Efficacy Of Merck Drug On HIV Reservoirs
Patients who added Merck"s HIV drug Isentress to their regular daily HIV drug regimen "fared no better than those who added a placebo to the mix," as the drug failed to "reduce low-level reservoirs of HIV," in the body, according to findings presented at the International AIDS Society conference in Cape Town, South Africa, Bloomberg reports. As part of the 53-participant study led by Harvard University, researchers looked at patients whose viral loads were at undetectable levels and "were given either Isentress or a placebo for 12 weeks, then switched to the alternate agent for an additional 12 weeks. The study found no difference in low levels of the virus between the two groups, using a highly sensitive test," the article states. "The results are a setback for doctors looking for ways to seek and destroy the last vestiges of HIV, which aren"t reached by currently available drugs. Eliminating these so-called viral reservoirs may potentially cure patients, allowing them to stop taking daily medicines," according to Bloomberg (Pettypiece, 7/22).
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Immune Genes Adapt To Parasites
Thank parasites for making some of our immune proteins into the inflammatory defenders they are today, according to a population genetics study that will appear in the June 8 issue of the Journal of Experimental Medicine (online May 25). The study, conducted by a team of researchers in Italy, also suggests that you might blame parasites for sculpting some of those genes into risk factors for intestinal disorders.
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Kaiser Daily Health Policy Report Feature Highlights Recent Blog Entries
"Blog Watch" offers readers a roundup of health policy-related blog posts.Appropriately, the last of the Senate Finance Committee"s three major public roundtables on health reform issues was on finance. Keith Hennessy lauds economist Kate Baicker"s testimony (.pdf) and says it helps connect reform ideas to a system of third-party payment. Hennessy says the current system leads people to "spend more of other people"s money than they do of their own, and less wisely." Hennessy explores the example of employer-sponsored insurance, which he says makes health insurance appear less expensive to employees than it is.Meanwhile, the New Republic"s Jonathan Cohn, who has been calling attention to potential ways of financing the significant cost of reform, recommends the testimony of Center on Budget and Policy Priorities President Robert Greenstein. Greenstein testified that there are no "painless" ways of raising money for reform, and said, "This leads to my first recommendation, in the form of a plea to the Committee. Please do not take any offset options off the table at this time. I believe you ultimately will need to put together a package that contains an array of spending and revenue offsets." Offsets could include removing or limiting the tax exclusion for employer-sponsored insurance. Bob Lazsewski strenuously disagrees. He illustrates a post titled "Paying for a Big Part of Health Care Reform With New Taxes Would Be a Terrible Mistake!" with a graph of the trends in health insurance premiums over the last 20 years and says, "paying for most of health care reform by raising taxes would be nothing less than cowardly and fiscally irresponsible." He continues, "the Congress is so desperate to find money and so unwilling to anger any powerful health care special interests we better get ready for some interesting rationalizations to promote tax increases in the place of fundamental reforms."After the hearing, ranking member Sen. Mike Enzi (R-Wyo.) gave a presentation at the Heritage Foundation on his preferences for bipartisan reform legislation and the Foundry"s Marguerite Higgins blogged Enzi"s key points. She says the senator wants to increase affordability, use private plans for coverage and ensure a bill is fully paid for.The White House appears to be initiating additional outreach efforts to mobilize support. Jose Antonio Vargas of the Washington Post"s Daily Dose reports that President Obama"s administration chose to send its first WhiteHouse.gov e-mail on health reform Wednesday. Vargas says, "It"s only fitting that Obama"s first official e-mail from the White House is about health care reform. As early as December, the incoming Obama administration began using new media tools to build grassroots support around the issue."Interesting elsewhere:
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British Medical Association Comment On Announcement On NHS Treatment Centres

The Department of Health announced that the terms offered to independent providers of treatment centres in the NHS in England will in future be more similar to those offered to NHS providers. Commenting on the announcement, Dr Hamish Meldrum, Chairman of Council at the BMA, says: "Millions of pounds" worth of taxpayers" money has been wasted because of the government"s determination to encourage the private sector into our NHS. When the first wave of these contracts comes to an end next year, the majority of independent providers will have failed to deliver the amount of work they have been paid for. "It"s a shame it"s taken so long to get an acknowledgement that skewing the playing field in favour of private companies has been unfair and wasteful. Independent sector treatment centres have been able to cherry-pick "easier" cases, potentially destabilising existing services. Even in future, private companies will be at an advantage because when things go wrong with a patient"s care, it"s the NHS that picks up the tab. "Especially in the current climate, the NHS cannot afford poor value contracts, unnecessary competition, and duplication of services. We need much more of a whole-systems approach to the provision of healthcare, and we need the NHS to be run on the basis of co-operation collaboration, not competition." Notes 1) View a BMA briefing paper on ISTCs here. 2) The BMA is currently raising awareness of the implications of NHS market reforms through its "Look After Our NHS campaign": http://lookafterournhs.org.uk British Medical Association


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