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Can-Fite-Completed Patient Enrollment For The Phase II Trial In Psoriasis With CF101
Can-Fite BioPharma (TASE:CFBI), a biotechnology company traded on the Tel Aviv Stock Exchange, has achieved yet another goal by completion of patients" enrollment in its phase II Psoriasis trial. Approximately 70 patients were enrolled to this study, randomized into 4 groups treated with 1, 2 and 4 mg of CF101 and placebo. Patients are taking the drug for 12 weeks plus 2 weeks of follow-up. The trial is being conducted in 10 sites in Israel and Europe. The company estimates to release study data on Q3 2009.
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Function Of Key Protein In Cancer Spread Described By LSUHSC Researchers
Research led by David Worthylake, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, may help lay the groundwork for the development of a compound to prevent the spread of cancer. The research will be published in the May 29, 2009 issue of the Journal of Biological Chemistry.
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Tamed Virus Wipes Out Cancer Safely
Cancer Research UK scientists have tamed a virus so that it attacks and destroys cancer cells but does not harm healthy cells, according to a paper published in PLoS Pathogens*.
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Alzheimer's Society Comment On New Tau Tangle Research

Tau protein tangles are found in the brains of people with a range of neurodegenerative diseases, including Alzheimer"s. New research published in Nature Cell Biology suggests that tangle formation can be transferred from one type of trans genetic mouse line to another. The research was carried out using two different mouse lines, one generated specifically to express a mutated form of human tau known to cause tangles and disease, the other generated to express normal human tau. Ordinary (wild type) mice do not have a type of tau that can make tangles. More research is needed to understand the implications of these results. "The observation that tangle formation can be transferred from one type of trans genetic mouse line to another is certainly exciting and may change the way we think about tangle formation in diseases such as Alzheimer"s. However, the research was carried out using two different trans genetic mouse lines and we will need a lot more research before we understand the implications of these observations. There is still so much we do not understand about the changes in tau that lead to tangle formation in humans and, eventually, widespread brain cell death. Each new piece of knowledge helps build a better picture and takes us closer to the point where we can stop loss of brain tissue and dementia for good." Dr Susanne Sorensen Head of Research Alzheimer"s Society Reference: Clavaguera F et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nature Cell Biology, published online 7 June 2009 Notes - One in three people over 65 will die with dementia. - Alzheimer"s Society research shows that 700,000 people in the UK have a form of dementia, more than half have Alzheimer"s disease. In less than 20 years nearly a million people will be living with dementia. This will soar to 1.7 million people by 2051. - Alzheimer"s Society champions the rights of people living with dementia and the millions of people who care for them. - Alzheimer"s Society works in England, Wales and Northern Ireland. - Alzheimer"s Society needs to raise money to help people live well with dementia today and for research to find a cure for tomorrow. You can donate now by calling 0845 306 0898 or visiting http://www.alzheimers.org.uk Alzheimer"s Society


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