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High Risk Of Dementia For Middle-Aged People Living Alone
Middle-aged people living alone have twice the risk of developing dementia and Alzheimer"s disease in later life compared with married or cohabiting people, while being widowed or divorced in mid-life carries three times the risk, according to a study led by Miia Kivipelto from the Swedish medical university Karolinska Institutet and published on http://www.bmj.com.
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Bacteria Pack Their Own Demise
Numerous pathogens contain an "internal time bomb", a deadly mechanism that can be used against them. After years of work, VIB researchers at the Vrije Universiteit Brussel (VUB) were able to determine the structure and operating mechanism of the proteins involved. This clears the road for finding ways to set the clock on this internal time bomb and, hopefully, in the process developing a new class of antibiotics. The research was accepted for publication by top journal Molecular Cell, with congratulations from the editorial board.
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Immune Genes Adapt To Parasites
Thank parasites for making some of our immune proteins into the inflammatory defenders they are today, according to a population genetics study that will appear in the June 8 issue of the Journal of Experimental Medicine (online May 25). The study, conducted by a team of researchers in Italy, also suggests that you might blame parasites for sculpting some of those genes into risk factors for intestinal disorders.
Endocrinology

ASGS Issues Position Statement Supporting TIF Natural Orifice Surgery For GERD

EndoGastric Solutions (EGS), the recognized leader in the emerging field of Natural Orifice Surgery (NOS), announced that the American Society of General Surgeons (ASGS) has published a position statement endorsing its Transoral Incisionless Fundoplication (TIF) procedure for the treatment of GERD. ASGS is the preeminent society of general surgeons with membership exceeding 2,000. In the position statement published on the society"s website , ASGS" Board of Trustees states, "transoral incisionless fundoplication (TIF) stands in sharp contrast to other natural orifice options in that it adheres to the fundamental surgical principle, which has guided surgical care for GERD for more than 50 years; specifically the creation of a full thickness gastric fundoplication in support of the lower esophageal sphincter." Based in part on the results of recently published scientific information on the long-term efficacy and durability of the TIF fundoplication procedure (Cadiere et al, Surgical Endoscopy, March 2009), the statement continues, "In clinical studies the TIF procedure has been shown to offer comparable results to more traditional procedures in the treatment of selected patients with GERD." "Surgical care is a continuously evolving healing art, and the pursuit of excellence demands that we continuously evaluate new innovations," explained Robert Sewell, MD, immediate past president of ASGS . "ASGS is excited by the prospect of natural orifice surgery"s ability to further revolutionize the way we treat our patients. One example of such an innovation is the new TIF antireflux procedure, which appears to offer results that are comparable to more invasive techniques. Tens of millions of patients in the U.S. suffer with a variety of symptoms associated with GERD, and many of them would be better served by surgical treatment. Any such treatment must be both effective and able to be performed with the lowest possible risk." "This position statement is an important development in the adoption of natural orifice surgery and TIF specifically," commented Thierry Thaure, President and Chief Executive Officer of EndoGastric Solutions. "TIF is gaining acceptance among ASGS members and non-member general surgeons throughout the U.S. and is on the cusp of broad adoption. ASGS" endorsement will support EGS" ongoing efforts in surgeon training, reimbursement and patient awareness as we invest in making TIF the standard of care in GERD treatment." EndoGastric Solutions®


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